Deployment of Microsoft Help 2.x files is more complex than HTML Help 1.x files as Microsoft Help 2.x files must be registered on the target machine in order that they can be viewed. In addition to registration, the help file must be 'Plugged-In' to the Visual Studio help collection in order to integrate with the Visual Studio help contents, index, or dynamic Help System. 

Document! X includes a command line tool, InnovaHxReg, which can be used to deploy Help 2.x files.